Research 🇬🇧 Directly KS related

[Video] Modeling KMT2C and EHMT1 Haploinsufficiency in Human Cortical Organoids | Dr. George Chen

person Dr. George Chen, Children's Hospital Los Angeles; IDefine

calendar_today Aug 6, 2026

Dr. George Chen presents lab research using human cortical organoids—3D cell models of early brain development—to model haploinsufficiency, where one working gene copy is not enough, in KMT2C and EHMT1. Because EHMT1 changes cause Kleefstra syndrome, the talk is directly relevant to KS biology, but the page does not establish a treatment or clinical finding.