Research 🇬🇧 Important for Genetic Diseases generally

Researchers Develop New Way to Safely Insert Gene-Sized DNA Into the Genome

person Mass General Brigham

calendar_today Mar 11, 2026

Mass General Brigham researchers report INSTALL, a non-toxic, virus-free genome writing approach that inserts large healthy DNA sequences using immune-evasive single-stranded DNA circles and recombinases. The method worked in human cells and mouse liver, suggesting future potential for scalable therapies for genetic diseases.