Scientific Article 🇬🇧 Mentions KS

Exome Analysis of Women with Early Onset Breast Cancer and Previous Uninformative Cancer Panel Genetic Testing

person Cecelie Rose Collins

calendar_today Aug 8, 2026

A 2026 Ohio State University thesis explored KMT2C, the gene associated with Kleefstra syndrome type 2, as a possible breast cancer predisposition gene. Two KMT2C variants were identified in women with early-onset breast cancer, including one previously reported in people with Kleefstra-like features. Evidence remains conflicting, and the study stresses that more research is needed before any cancer-risk link can be established.