Epigenetic Insights and Exosome-Based Therapeutics for Insomnia: Bridging Sleep Biology and Precision Medicine

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This review explores how epigenetic mechanisms regulate sleep and how exosomes—tiny packages released by cells—could support future insomnia diagnostics and treatment. It explicitly discusses EHMT1 and Kleefstra syndrome as an example linking altered chromatin regulation to sleep problems. It does not establish an exosome treatment for KS.

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